In homeopathy, certain remedies are known to be predominantly aggravated by either cold or heat. This classification helps practitioners understand the conditions under which a remedy is more effective or less effective, guiding treatment plans for individuals based on their specific sensitivities. In homeopathy, certain remedies exhibit a side affinity, meaning they have a tendency to affect one side of the body more than the other. This characteristic is crucial for practitioners when diagnosing and prescribing treatments.